rogain&facial aging

[tacolinowest]

does using this stuff age your face? i had no idea this could happen i was just reading about alot of people experiencing this, how could this be? if you stop, will those effects go away?

[greatjob]

minoxidil has been found to inhibit gene expression of the enzyme lysyl hydroxylase which is involved in the production of collagen, so it can increase wrinkles and skin aging

[tacolinowest]

is it reversible, i been using it for prob 7 years, so i started when i was 18ish? and thought that i had these wrinkles in my forehead from genetics,, is it reversible? if i stop will it get better?

[greatjob]

Well there is really no way to definitively say that those wrinkles are from minoxidil use. If you stop using minoxidil the enzyme will stop being inhibited, but if minox did cause the wrinkles they aren't going to go away just because you stopped, so no if the wrinkles were caused by minox it is not reversible by stopping use. I have wrinkles on my forehead which are expression lines, my mom has the exact same lines, so I know I would have them no matter what because they have always been there. Minoxidil may have exacerbated the problem, but I am ok due to risk vs reward. I haven't seen any studies about whether or not the enzyme inhibition is localized to the area of application or if it is widespread due to systemic absorption so I really don't know if it is having any effect on collagen production anywhere except on top of my head. Like propecia you have to weigh the risks vs reward and decide if you are comfortable with them.